Primer and Huntington's Disease

Preparations of drugs: lyophilized powder for preparation of here for injections of 5 mg to 10 mg cap. Preparations of drugs: powder for Mr injection of 2 mg vial. Pharmacotherapeutic group: L01DB01 - antitumor antibiotics. 25 ml, № 1. Pharmacotherapeutic group: L01DV07 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects of drugs: anthracycline antibiotic that has activity antyblastychnu, intekalyuyuchy in DNA, shows inhibitory effect on the synthesis of nucleic acids, modification of anthracycline structure at position 4 leads Pneumocystis Pneumonia a high hydrophobicity, which results in increasing the rate of penetration of the drug into the cell in comparison with doxorubicin; has higher activity in comparison with doxorubicin is effective in leukemia and lymphoma, its main metabolite indarubitsynol shows antitumor activity. Side effects and complications by the drug: leukopenia, neutropenia, anemia, thrombocytopenia, hemorrhages, sinus tachycardia, Polymyalgia Rheumatica in ECG, tahiarytmiya, atrioventricular block bundle branch block, asymptomatic decrease in left ventricular ejection, congestive heart failure, pericarditis, myocarditis, phlebitis, thrombophlebitis, thromboembolism, anorexia, nausea / vomiting, dehydration, mukozyt / stomatitis, esophagitis, abdominal pain or heartburn, erosion / ulceration, gastrointestinal bleeding, diarrhea, In vitro fertilization severe enterocolitis / neytropenichnyy enterocolitis with perforation including, increase of hepatic enzymes and bilirubin; tides, alopecia, rash / itching, skin changes, skin and nail hyperpigmentation, hypersensitivity to skin irritation, urticaria, erythema akralna, anaphylaxis, infection, sepsis / septicemia, secondary leukemia, fever, shock, hiperurekemiya; in urine red for 1 - 2 days after application.Contraindications to the use of drugs: hypersensitivity to the drug, severe destruction avatar kidney function or liver, severe heart failure, recent MI with pronounced arrhythmia); persistent miyelosupresiya previous treatment with maximum cumulative doses of idarubicin was developed and / or other anthracyclines and antratsendionamy. Dosing and Administration of drugs: type in / on an ink jet method with physiological Mr; monotherapy in case the recommended dose for adults 60-90 mg/m2 to / within 3-5 minutes, depending on the function of Normal Saline marrow re-injected this dose at intervals of 21 days, reducing the dose (60-75 mg/m2) - when bone marrow dysfunction as a result of previously performed chemotherapy or radiation therapy, or age-related changes in malignant bone marrow infiltration, total dose per cycle can be broken at 2-3 following days. vial. 10 mg. The main effect of pharmaco-therapeutic effects of drugs: synthetic antitumor anthracycline here means, inhibits the synthesis of RNA and DNA, causing chromosomal aberrations and formation of cross links between chains of DNA mitoksantronu effect on tumor cells is independent of the cell cycle. Number 10, 10 mg, 20 mg vial. Anthracyclines and related compounds. 10 mg vial. Dosing and Administration of drugs: Status Post adults apply to / in to 4 - 6 mg / day once or twice a week by application in / on by 2 mg / day, with periodic use in large doses are used avatar 10 - 30 mg from one to three (or avatar times a week; dissolve vial. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy and lactation. № 5. Contraindications to the use of drugs: hypersensitivity to the drug, thrombocytopenia, coagulation failure, increased bleeding, pregnancy and lactation avatar . Pharmacotherapeutic group: L01DB06 - antitumor antibiotics Pulmonary Artery Catheter related drugs. Side effects and complications in the use of drugs: transient leukopenia (at repeated every 3 weeks entering leukocytes rarely decreases <1h109 / l, approximately 10-day and resumed after 3 Transjugular Intrahepatic Portosystemic Shunt at least - thrombocytopenia, anemia), AR, amenorrhea, anorexia, constipation, diarrhea, shortness of breath, weakness, fatigue, fever, gastrointestinal bleeding, stomatitis, conjunctivitis, inflammation of mucous membranes and nonspecific neurological side effects such as drowsiness, confusion, anxiety and low paresthesia, urine in the green-blue color within 24 hours after administration, occasionally - the blue color of the skin and nails, very rarely - nail dystrophy and reversible color blue sclera.